CHA Family Medicine Residency

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Quinolones and FDA

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FDA: Quinolones are mo’ bad.

http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm500665.htm

Avoid antibiotics in general. Right?

Nitrofurantoin seems generally ok for UTI, but some elders weird-out on that as well.

Macrolides can kill you. Suddenly. Rarely. Especially azithro. QTc and whatnot.

Amoxicillin, cephalosporins of course are options.

Doxycycline is sometimes forgotten as an option for respiratory/cutaneous/GI/GU infections. Don’t go in the sun.

SXT-TMP (Bactrim) – effective for a lot of infections, but E coli often resistant.

Consider IM ceftriaxone for elderly in nursing home with UTI

 

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Author: gemaxted

Associate Program Director Tufts University Family Medicine Residency at Cambridge Health Alliance

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